Use of somatostatin analog in management of carcinoid syndrome
نویسندگان
چکیده
منابع مشابه
The use of somatostatin analog in gastroenteropancreatic tumors other than carcinoid.
We have used the gastrinoma syndrome to examine the effects of SMS. Acutely, SMS decreased acid secretion and restored the BAO/MAO to normal in eight of eight patients. Basal and secretin-stimulated gastrin responses were suppressed but not normalized. Treatment for up to 2 years with SMS controlled symptoms, suppressed serum gastrin, and suppressed acid secretion. Treatment for 1 year or longe...
متن کاملUse of somatostatin analog for localization and treatment of ACTH secreting bronchial carcinoid tumor.
A 29-year-old woman presenting with an ectopic adrenocorticotropic hormone syndrome and a nodule of the upper lobe of the left lung was explored by indium 111 (111In) octreotide scintigraphy. This showed a pathologic uptake by the nodule. Treatment with octreotide resulted in the rapid control of hypercortisolism prior to surgery.
متن کاملSomatostatin, gastrointestinal peptides, and the carcinoid syndrome.
During a control infusion noradrenaline and alcohol each provoked carcinoid flushing in four of five patients and pentagastrin in two of five patients. When tetradecapeptide somatostatin was infused on another day no patient flushed at any time, even when 16 microgram of either noradrenaline or pentagastrin were administered. Carcinoid flushing was not associated with release of gastrin or any ...
متن کاملManagement of carcinoid syndrome.
Carcinoid tumours are uncommon neoplasms with a reported incidence of 1.5 per 100 000 population. Although they can develop in any organ derived from primitive endoderm, they occur most frequently in the appendix. Primary carcinoid tumours can be classified according to their site of origin. Although this classification into fore-gut, mid-gut or hind-gut tumours is of no prognostic significance...
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ژورنال
عنوان ژورنال: Digestive Diseases and Sciences
سال: 1989
ISSN: 0163-2116,1573-2568
DOI: 10.1007/bf01536042